The Hedrin Family

Hedrin® Once

A fast acting solution that takes just
15 minutes to work.

Hedrin® Protect & Go

A hassle-free conditioning spray, clinically proven to help protect against head lice.

Hedrin® Treat & Go Spray

A fuss-free solution great for children who
just won't sit still.

Hedrin® Treat & Go Mousse

Kills head lice & eggs, no fuss.

Hedrin® Dual Pack

A handy protective & treatment in one pack. Contains Hedrin Protect & Go and Hedrin Treat & Go

How does Hedrin work?

Hedrin’s efficacy is a result of its ingredients, Dimeticone (Hedrin 4% Lotion and Hedrin Once), Activdiol (Hedrin Treat & Go and Protect & Go.) Hedrin formulations are patented and have been shown to be effective at killing head lice in clinical trials.


Head lice have a unique strategy of water management. Instead of producing urine they eliminate excess water via tiny passages in their exoskeleton called spiracles. The active ingredient Dimeticone, a silicone oil, disrupts this process of water management by coating the lice, causing them to become permanently immobile, and blocking the spiracles preventing them from getting rid of excess water. As a result, any lice that have recently fed suffer from death by gut rupture and, the ones that haven’t, die of starvation.


Like all insects, head lice are covered by a waxy protective coating. It is this waxy layer that helps the louse maintain its delicate internal water balance, preventing too much water from evaporating. The Activdiol® in Hedrin works dissolving away this waxy cuticle, causing death by dehydration. Activdiol is available in treatment strength (5%) or protection strength (1%).